Assay Detail
Binding
CHEMBL660795
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Cyclin-dependent kinase 1
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
Imidazo[1,2-a]pyridines. Part 2: SAR and optimisation of a potent and selective class of cyclin-dependent kinase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.02 | 8.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL73243 | — | — | 1 | 8.22 |
| CHEMBL72548 | — | — | 1 | 7.82 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL73243 | — | IC50 | = | 6.0 | nM | 8.22 |
| CHEMBL72548 | — | IC50 | = | 15.0 | nM | 7.82 |