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Assay Detail

CHEMBL661059

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity for the cannabinoid brain receptor (CB1) using [3H]CP-55940
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Cannabinoid receptor 1 (CHEMBL3571)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

Enantioselective synthesis and pharmacology of 11-hydroxy-(1'S,2'R)-dimethylheptyl-delta 8-THC.
Liddle J, Huffman JW, Wiley JL, Martin BR.
Bioorg Med Chem Lett (1998) 8 : 2223 -2226
PubMed 9873517 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 3 9.25 9.34

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL71401 1 9.34
CHEMBL73060 1 9.31
CHEMBL411626 1 9.11

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL71401 Ki = 0.46 nM 9.34
CHEMBL73060 Ki = 0.49 nM 9.31
CHEMBL411626 Ki = 0.77 nM 9.11