Assay Detail
Binding
CHEMBL661063
Review assay metadata, readout intent, target linkage, and publication context from the same page.
The affinity of compound for the cannabinoid brain receptor was determined by measuring its ability to displace [3H]CP-55940 from its binding site in a membrane preparation
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Synthesis and pharmacology of the 1,2-dimethylheptyl-8-THC isomers: exceptionally potent cannabinoids
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 8.91 | 9.34 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL330379 | — | — | 1 | 9.34 |
| CHEMBL317086 | — | — | 1 | 9.22 |
| CHEMBL307696 | — | — | 1 | 9.14 |
| CHEMBL411626 | — | — | 1 | 9.11 |
| CHEMBL328588 | — | — | 1 | 9.09 |
| CHEMBL328108 | — | — | 1 | 9.08 |
| CHEMBL267227 | DELTA-8-TETRAHYDROCANNABINOL | 2.0 | 1 | 7.36 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL330379 | — | Ki | = | 0.46 | nM | 9.34 |
| CHEMBL317086 | — | Ki | = | 0.6 | nM | 9.22 |
| CHEMBL307696 | — | Ki | = | 0.73 | nM | 9.14 |
| CHEMBL411626 | — | Ki | = | 0.77 | nM | 9.11 |
| CHEMBL328588 | — | Ki | = | 0.81 | nM | 9.09 |
| CHEMBL328108 | — | Ki | = | 0.84 | nM | 9.08 |
| CHEMBL267227 | DELTA-8-TETRAHYDROCANNABINOL | Ki | = | 44.0 | nM | 7.36 |