Assay Detail
Binding
CHEMBL661064
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Binding affinity against the cannabinoid receptor
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Structural requirements for binding of anandamide-type compounds to the brain cannabinoid receptor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 7.14 | 8.14 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL429055 | — | — | 1 | 8.14 |
| CHEMBL277297 | — | — | 1 | 7.89 |
| CHEMBL15566 | — | — | 1 | 7.52 |
| CHEMBL423382 | — | — | 1 | 7.39 |
| CHEMBL160717 | — | — | 1 | 6.66 |
| CHEMBL121229 | — | — | 1 | 6.22 |
| CHEMBL75591 | — | — | 1 | 6.19 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL429055 | — | Ki | = | 7.3 | nM | 8.14 |
| CHEMBL277297 | — | Ki | = | 13.0 | nM | 7.89 |
| CHEMBL15566 | — | Ki | = | 30.0 | nM | 7.52 |
| CHEMBL423382 | — | Ki | = | 41.0 | nM | 7.39 |
| CHEMBL160717 | — | Ki | = | 220.0 | nM | 6.66 |
| CHEMBL121229 | — | Ki | = | 598.0 | nM | 6.22 |
| CHEMBL75591 | — | Ki | = | 650.0 | nM | 6.19 |