Assay Detail
Binding
CHEMBL661081
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Compound was evaluated for the inhibition of Cathepsin B
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Novel peptidyl alpha-keto amide inhibitors of calpains and other cysteine proteases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 5.19 | 5.34 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL419590 | — | — | 1 | 5.34 |
| CHEMBL331850 | — | — | 1 | 5.03 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL419590 | — | Ki | = | 4600.0 | nM | 5.34 |
| CHEMBL331850 | — | Ki | = | 9300.0 | nM | 5.03 |