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Assay Detail

CHEMBL661955

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
The compound was tested for the cytotoxicity DC-3F cell lines
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Cricetulus griseus
Cell Type DC3F
Confidence 1 — Organism
Curated By Intermediate

Target

DC3F (CHEMBL612702)
Type CELL-LINE
Organism Cricetulus griseus

Publication

9-substituted acridine derivatives with long half-life and potent antitumor activity: synthesis and structure-activity relationships.
Su TL, Chou TC, Kim JY, Huang JT, Ciszewska G, Ren WY, Otter GM, Sirotnak FM, Watanabe KA.
J Med Chem (1995) 38 : 3226 -3235
PubMed 7650675 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.40 8.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL43 AMSACRINE 4.0 1 8.40

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL43 AMSACRINE IC50 = 4.0 nM 8.40