Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL661959

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Tested for the inhibition of specific [3H]propionyl-CCK-8 binding to guinea pig cortical Cholecystokinin type A receptor
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Cavia porcellus
Confidence 9 — Direct single protein target
Curated By Intermediate

Target

Cholecystokinin receptor type A (CHEMBL3501)
Type SINGLE PROTEIN
Organism Cavia porcellus

Publication

Pseudopeptide CCK-4 analogues incorporating the [CH(CN)NH] peptide bond surrogate
Herrero S, Suarez-Gea M, Gonzalez-Muniz R, Garcia-Lopez M, Herranz R, Ballaz S, Barber A, Fortuno A, Del Rio J
Bioorg Med Chem Lett (1997) 7 : 855 -860
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.58 5.75

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL64605 1 5.75
CHEMBL169054 1 5.40

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL64605 IC50 = 1800.0 nM 5.75
CHEMBL169054 IC50 = 4000.0 nM 5.40