Assay Detail
Binding
CHEMBL662006
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of bovine adrenal desmolase
3
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bos taurus |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Target
Cholesterol side-chain cleavage enzyme, mitochondrial (CHEMBL4813) ↗| Type | SINGLE PROTEIN |
| Organism | Bos taurus |
Publication
Synthesis and aromatase inhibition of 3-cycloalkyl-substituted 3-(4-aminophenyl)piperidine-2,6-diones.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.27 | 4.54 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL488 | AMINOGLUTETHIMIDE | 4.0 | 1 | 4.54 |
| CHEMBL70901 | — | — | 2 | 4.17 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL488 | AMINOGLUTETHIMIDE | IC50 | = | 29000.0 | nM | 4.54 |
| CHEMBL70901 | — | IC50 | = | 67000.0 | nM | 4.17 |
| CHEMBL70901 | — | IC50 | = | 82000.0 | nM | 4.09 |