Assay Detail
Binding
CHEMBL662656
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Compound was evaluated for aspartyl protease inhibition selectivity relative to Cathepsin D
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Peptidomimetic inhibitors of human immunodeficiency virus protease (HIV-PR): Design, enzyme binding and selectivity, antiviral efficacy, and cell permeability properties
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 7.47 | 8.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL167514 | — | — | 1 | 8.70 |
| CHEMBL166175 | — | — | 1 | 7.00 |
| CHEMBL165706 | — | — | 1 | 6.70 |
| CHEMBL3350189 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL167514 | — | Ki | = | 2.0 | nM | 8.70 |
| CHEMBL166175 | — | Ki | = | 100.0 | nM | 7.00 |
| CHEMBL165706 | — | Ki | = | 200.0 | nM | 6.70 |
| CHEMBL3350189 | — | Ki | > | 1000.0 | nM | - |