Assay Detail
Functional
CHEMBL662768
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of cell growth was studied in chinese hamster lung cells resistant to actinomycin D (DC-3F/AD-II).
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cricetulus griseus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Cyclopent[a]anthraquinones as DNA intercalating agents with covalent bond formation potential: synthesis and biological activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.20 | 6.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL105 | MITOMYCIN | 4.0 | 1 | 6.96 |
| CHEMBL94680 | — | — | 1 | 5.44 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL105 | MITOMYCIN | IC50 | = | 110.0 | nM | 6.96 |
| CHEMBL94680 | — | IC50 | = | 3600.0 | nM | 5.44 |