Assay Detail
Functional
CHEMBL662770
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The compound was tested for the cytotoxicity against human leukemic DC-3F/ADII cell lines, activity is expressed as IC50 values.
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | DC3F/AD-II |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
9-substituted acridine derivatives with long half-life and potent antitumor activity: synthesis and structure-activity relationships.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.30 | 7.33 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL43 | AMSACRINE | 4.0 | 1 | 7.33 |
| CHEMBL321473 | — | — | 1 | 7.27 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL43 | AMSACRINE | IC50 | = | 47.0 | nM | 7.33 |
| CHEMBL321473 | — | IC50 | = | 54.0 | nM | 7.27 |