Assay Detail
Binding
CHEMBL662883
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Concentration required for the inhibitory activity against human Cell division cycle 25A
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Synthesis of a novel class of cdc25A inhibitors from vitamin D3.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 4.67 | 5.11 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL332036 | — | — | 1 | 5.11 |
| CHEMBL156968 | — | — | 1 | 5.05 |
| CHEMBL158314 | — | — | 1 | 4.50 |
| CHEMBL157936 | — | — | 1 | 4.03 |
| CHEMBL345921 | — | — | 1 | - |
| CHEMBL155993 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL332036 | — | IC50 | = | 7700.0 | nM | 5.11 |
| CHEMBL156968 | — | IC50 | = | 9000.0 | nM | 5.05 |
| CHEMBL158314 | — | IC50 | = | 32000.0 | nM | 4.50 |
| CHEMBL157936 | — | IC50 | = | 94000.0 | nM | 4.03 |
| CHEMBL345921 | — | IC50 | > | 300000.0 | nM | - |
| CHEMBL155993 | — | IC50 | > | 300000.0 | nM | - |