Assay Detail
Binding
CHEMBL662884
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Concentration required to inhibit human Cell division cycle 25A activity
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Design and synthesis of dysidiolide analogs from vitamin D3: novel class of Cdc25A inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.85 | 6.36 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL109990 | — | — | 1 | 6.36 |
| CHEMBL111717 | — | — | 1 | 6.32 |
| CHEMBL109588 | — | — | 1 | 6.07 |
| CHEMBL110952 | — | — | 1 | 6.05 |
| CHEMBL332036 | — | — | 1 | 5.26 |
| CHEMBL1765353 | DYSIDIOLIDE | — | 1 | 5.03 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL109990 | — | IC50 | = | 440.0 | nM | 6.36 |
| CHEMBL111717 | — | IC50 | = | 480.0 | nM | 6.32 |
| CHEMBL109588 | — | IC50 | = | 860.0 | nM | 6.07 |
| CHEMBL110952 | — | IC50 | = | 890.0 | nM | 6.05 |
| CHEMBL332036 | — | IC50 | = | 5500.0 | nM | 5.26 |
| CHEMBL1765353 | DYSIDIOLIDE | IC50 | = | 9400.0 | nM | 5.03 |