Assay Detail
Binding
CHEMBL662890
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The compound was tested for its inhibitory activity against Cell division cycle 25A
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Synthesis of the novel analogues of dysidiolide and their structure-activity relationship.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.75 | 4.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL86406 | — | — | 1 | 4.89 |
| CHEMBL356927 | — | — | 1 | 4.82 |
| CHEMBL313595 | — | — | 1 | 4.82 |
| CHEMBL1765353 | DYSIDIOLIDE | — | 1 | 4.46 |
| CHEMBL86451 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL86406 | — | IC50 | = | 13000.0 | nM | 4.89 |
| CHEMBL356927 | — | IC50 | = | 15000.0 | nM | 4.82 |
| CHEMBL313595 | — | IC50 | = | 15000.0 | nM | 4.82 |
| CHEMBL1765353 | DYSIDIOLIDE | IC50 | = | 35000.0 | nM | 4.46 |
| CHEMBL86451 | — | IC50 | > | 300000.0 | nM | - |