Assay Detail
Binding
CHEMBL663080
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Tested for the inhibition of [3H]pCCK-8 to Cholecystokinin type B receptor in guinea pig brain
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Cavia porcellus |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Gastrin/cholecystokinin type B receptor (CHEMBL298) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Structure-based design and pharmacological properties of potent selective and systemically active CCK-B peptidomimetics
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 8.39 | 10.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL262894 | — | — | 1 | 10.22 |
| CHEMBL412917 | — | — | 1 | 9.34 |
| CHEMBL353862 | — | — | 1 | 7.85 |
| CHEMBL436722 | — | — | 1 | 7.41 |
| CHEMBL171594 | — | — | 1 | 7.15 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL262894 | — | Ki | = | 0.06 | nM | 10.22 |
| CHEMBL412917 | — | Ki | = | 0.46 | nM | 9.34 |
| CHEMBL353862 | — | Ki | = | 14.0 | nM | 7.85 |
| CHEMBL436722 | — | Ki | = | 39.0 | nM | 7.41 |
| CHEMBL171594 | — | Ki | = | 71.0 | nM | 7.15 |