Assay Detail
Binding
CHEMBL663083
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Binding affinity (affinity state 1) for Cholecystokinin type B receptor, was determined using CHO cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Cavia porcellus |
| Cell Type | CHO |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Gastrin/cholecystokinin type B receptor (CHEMBL298) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Synthesis and biological properties of new constrained CCK-B antagonists: discrimination of two affinity states of the CCK-B receptor on transfected CHO cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 8.73 | 9.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL406359 | — | — | 1 | 9.30 |
| CHEMBL338525 | — | — | 1 | 8.72 |
| CHEMBL338300 | — | — | 1 | 8.17 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL406359 | — | Ki | = | 0.5 | nM | 9.30 |
| CHEMBL338525 | — | Ki | = | 1.9 | nM | 8.72 |
| CHEMBL338300 | — | Ki | = | 6.8 | nM | 8.17 |