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Assay Detail

CHEMBL663388

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Functional
Inhibition concentration against coxsackie virus A24
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Coxsackievirus
Confidence 1 — Organism
Curated By Intermediate

Target

Coxsackievirus (CHEMBL613750)
Type ORGANISM
Organism Coxsackievirus

Publication

Design, synthesis, and structure-activity relationship of pyridyl imidazolidinones: a novel class of potent and selective human enterovirus 71 inhibitors.
Shia KS, Li WT, Chang CM, Hsu MC, Chern JH, Leong MK, Tseng SN, Lee CC, Lee YC, Chen SJ, Peng KC, Tseng HY, Chang YL, Tai CL, Shih SR.
J Med Chem (2002) 45 : 1644 -1655
PubMed 11931618 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 6.30 6.33

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL296696 1 6.33
CHEMBL291183 1 6.26

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL296696 IC50 = 470.0 nM 6.33
CHEMBL291183 IC50 = 550.0 nM 6.26