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Assay Detail

CHEMBL663396

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Tested for inhibition of [3H]pCCK-8 specific binding to cholecystokinin type B receptor in guinea pig brain cortex
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Cavia porcellus
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Gastrin/cholecystokinin type B receptor (CHEMBL298)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Cholecystokinin peptidomimetics as selective CCK-B antagonists: design, synthesis, and in vitro and in vivo biochemical properties.
Blommaert AG, Weng JH, Dorville A, McCort I, Ducos B, Durieux C, Roques BP.
J Med Chem (1993) 36 : 2868 -2877
PubMed 8411002 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.05 7.05

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL95115 1 7.05

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL95115 Ki = 89.0 nM 7.05