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Assay Detail

CHEMBL663473

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Half-maximal inhibition of [125I]CCK-33 binding to cholecystokinin receptor
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Rattus norvegicus
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Cholecystokinin receptor type A (CHEMBL2798)
Type SINGLE PROTEIN
Organism Mus musculus

Publication

Methods for drug discovery: development of potent, selective, orally effective cholecystokinin antagonists.
Evans BE, Rittle KE, Bock MG, DiPardo RM, Freidinger RM, Whitter WL, Lundell GF, Veber DF, Anderson PS, Chang RS.
J Med Chem (1988) 31 : 2235 -2246
PubMed 2848124 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.47 5.47

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL70728 1 5.47

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL70728 IC50 = 3400.0 nM 5.47