Assay Detail
Binding
CHEMBL663986
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Inhibition of wild type cytochrome P450cam expressed in Escherichia coli
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
Computer-assisted design of selective imidazole inhibitors for cytochrome p450 enzymes.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.53 | 6.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL330775 | — | — | 1 | 6.10 |
| CHEMBL120057 | — | — | 1 | 5.82 |
| CHEMBL116766 | — | — | 1 | 5.40 |
| CHEMBL14192 | BENZYLIMIDAZOLE | — | 1 | 4.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL330775 | — | IC50 | = | 800.0 | nM | 6.10 |
| CHEMBL120057 | — | IC50 | = | 1500.0 | nM | 5.82 |
| CHEMBL116766 | — | IC50 | = | 4000.0 | nM | 5.40 |
| CHEMBL14192 | BENZYLIMIDAZOLE | IC50 | = | 16000.0 | nM | 4.80 |