Assay Detail
Binding
CHEMBL664121
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Inhibitory effect on the activity of calf thymus DNA polymerase alpha was determined by inhibitory dose curves
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bos taurus |
| Confidence | 3 — Cell-line / Tissue |
| Curated By | Intermediate |
Publication
Biotinylated lithocholic acids for affinity chromatography of mammalian DNA polymerases alpha and beta.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.44 | 4.54 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3138237 | — | — | 1 | 4.54 |
| CHEMBL3138225 | — | — | 1 | 4.40 |
| CHEMBL3138247 | — | — | 1 | 4.38 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3138237 | — | IC50 | = | 29000.0 | nM | 4.54 |
| CHEMBL3138225 | — | IC50 | = | 40000.0 | nM | 4.40 |
| CHEMBL3138247 | — | IC50 | = | 42000.0 | nM | 4.38 |