Assay Detail
Binding
CHEMBL665127
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Inhibitory activity against cephalosporinase from Proteus morganii TH-64 using cephalothin (40 uM) as a substrate
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Morganella morganii |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Synthesis and beta-lactamase inhibitory properties of 2 beta-[(1,2,3-triazol-1-yl)methyl]-2 alpha-methylpenam-3 alpha-carboxylic acid 1,1-dioxide and related triazolyl derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.41 | 6.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL285387 | — | — | 1 | 6.82 |
| CHEMBL403 | SULBACTAM | 4.0 | 1 | 6.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL285387 | — | IC50 | = | 150.0 | nM | 6.82 |
| CHEMBL403 | SULBACTAM | IC50 | = | 1000.0 | nM | 6.00 |