Assay Detail
Binding
CHEMBL665253
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Inhibitory activity against dihydrofolate reductase in Pneumocystis carinii in the prence of 100 micro M PABA.
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Pneumocystis carinii |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
New drug developments for opportunistic infections in immunosuppressed patients: Pneumocystis carinii.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.00 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL443 | SULFAMETHOXAZOLE | 4.0 | 1 | 7.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL443 | SULFAMETHOXAZOLE | IC50 | = | 100.0 | nM | 7.00 |