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Assay Detail

CHEMBL665381

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Compound was evaluated for binding affinity against Dopamine D2 receptor using radioligand binding assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

D(2) dopamine receptor (CHEMBL217)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Rs-100235: A high affinity 5-HT4 receptor antagonist
Clark R, Jahangir A, Flippin L, Langston J, Leung E, Bonhaus D, Wong E, Johnson L, Eglen R
Bioorg Med Chem Lett (1995) 5 : 2119 -2122
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 6.50 6.50

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL69733 1 6.50

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL69733 Ki = 316.23 nM 6.50