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Assay Detail

CHEMBL665804

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition constant at a concentration of 25 uM on calf DNA polymerase alpha as a function of template primer dose
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Bos taurus
Confidence 3 — Cell-line / Tissue
Curated By Intermediate

Target

Nucleic Acid (CHEMBL345)
Type NUCLEIC-ACID

Publication

Biotinylated lithocholic acids for affinity chromatography of mammalian DNA polymerases alpha and beta.
Watanabe M, Hanashima S, Mizushina Y, Yoshida H, Oshige M, Sakaguchi K, Sugawara F.
Bioorg Med Chem Lett (2002) 12 : 287 -290
PubMed 11814779 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 4.82 4.82

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3138225 1 4.82

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3138225 Ki = 15300.0 nM 4.82