Assay Detail
Binding
CHEMBL665890
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Tested for its selectivity against human Cholecystokinin type A receptor isolated from a human gallbladder cDNA library and stably transfected into a COSM6 cell line; (n=1)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Cell Type | COSM6 |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Novel 1,5-benzodiazepindione gastrin/CCKB antagonists
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 7.40 | 8.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL320624 | — | — | 1 | 8.00 |
| CHEMBL95200 | — | — | 1 | 7.10 |
| CHEMBL320141 | — | — | 1 | 7.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL320624 | — | Ki | = | 10.0 | nM | 8.00 |
| CHEMBL95200 | — | Ki | = | 79.43 | nM | 7.10 |
| CHEMBL320141 | — | Ki | = | 79.43 | nM | 7.10 |