Assay Detail
Binding
CHEMBL665957
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Compound was tested in vitro for inhibitory activity against chick optic lobe choline acetyltransferase (ChAT)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
(E)-1-alkyl-[2-(1H-azol-2-yl)vinyl]pyridinium salts: theoretical analysis, synthesis and evaluation of their interaction with choline acetyltransferase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.46 | 4.54 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL19537 | — | — | 1 | 4.54 |
| CHEMBL37827 | — | — | 1 | 4.43 |
| CHEMBL282920 | — | — | 1 | 4.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL19537 | — | IC50 | = | 29000.0 | nM | 4.54 |
| CHEMBL37827 | — | IC50 | = | 37000.0 | nM | 4.43 |
| CHEMBL282920 | — | IC50 | = | 40000.0 | nM | 4.40 |