Assay Detail

CHEMBL665979

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Functional

Tested for effect to cause relaxation of bovine coronary artery

ChEMBL ↗

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Target

Unchecked (CHEMBL612545) ↗

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Primary target Unchecked

CHEMBL612545

Anchored from Assay target.

Protein identity Unchecked

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Bos taurus
Tissue	Coronary artery
Confidence	0 — Uncurated / Unknown
Curated By	Autocuration

Target

Unchecked (CHEMBL612545) ↗

Type

UNCHECKED

Publication

10,10-Difluoro-13-dehydroprostacyclin: a chemically and metabolically stabilized potent prostacyclin.

Fried J, Mitra DK, Nagarajan M, Mehrotra MM.
J Med Chem (1980) 23 : 234 -237
PubMed 6988588 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
EC50	2	7.81	8.07

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL75692	—	—	1	8.07
CHEMBL1139	EPOPROSTENOL	4.0	1	7.55

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL75692	—	EC50	=	8.5	nM	8.07
CHEMBL1139	EPOPROSTENOL	EC50	=	28.0	nM	7.55