Assay Detail
Binding
CHEMBL666050
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In vitro binding affinity against Corticotropin releasing factor receptor in rat cortical homogenates
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Target
Corticotropin releasing factor receptor (CHEMBL2111360) ↗| Type | PROTEIN FAMILY |
| Organism | Rattus norvegicus |
Publication
Imidazo[4,5-b]pyridines as corticotropin releasing factor receptor ligands.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 9.09 | 9.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL431105 | — | — | 1 | 9.15 |
| CHEMBL283993 | — | — | 1 | 9.15 |
| CHEMBL276971 | — | — | 1 | 8.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL431105 | — | Ki | = | 0.7 | nM | 9.15 |
| CHEMBL283993 | — | Ki | = | 0.7 | nM | 9.15 |
| CHEMBL276971 | — | Ki | = | 1.1 | nM | 8.96 |