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Assay Detail

CHEMBL666576

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibitory activity against rat brain Dipeptidyl aminopeptidase using 10 nM of [3H]Leu-enkephalin as substrate
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

New bidentates as full inhibitors of enkephalin-degrading enzymes: synthesis and analgesic properties.
Fournié-Zaluski MC, Coulaud A, Bouboutou R, Chaillet P, Devin J, Waksman G, Costentin J, Roques BP.
J Med Chem (1985) 28 : 1158 -1169
PubMed 3897541 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.63 8.63

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL16457 1 8.63

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL16457 IC50 = 2.32 nM 8.63