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Assay Detail

CHEMBL666609

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Binding
Inhibition of Cyclin dependent kinase CDK4/B
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Expert

Target

Cyclin-dependent kinase 4 (CHEMBL331)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Identification of selective inhibitors of cyclin dependent kinase 4.
Carini DJ, Kaltenbach RF, Liu J, Benfield PA, Boylan J, Boisclair M, Brizuela L, Burton CR, Cox S, Grafstrom R, Harrison BA, Harrison K, Akamike E, Markwalder JA, Nakano Y, Seitz SP, Sharp DM, Trainor GL, Sielecki TM.
Bioorg Med Chem Lett (2001) 11 : 2209 -2211
PubMed 11514172 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.13 4.13

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL67655 1 4.13

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL67655 IC50 = 74500.0 nM 4.13