Assay Detail
Binding
CHEMBL668104
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory concentration against dihydrofolate reductace enzyme of Cryptosporidium parvum of human origin
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Cryptosporidium parvum |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
New 2,4-diamino-5-(2',5'-substituted benzyl)pyrimidines as potential drugs against opportunistic infections of AIDS and other immune disorders. Synthesis and species-dependent antifolate activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 4.52 | 4.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL34823 | — | — | 1 | 4.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL34823 | — | IC50 | = | 30000.0 | nM | 4.52 |