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Assay Detail

CHEMBL668375

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Affinity against D4 receptor was evaluated
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

D(4) dopamine receptor (CHEMBL219)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

NGB 2904 and NGB 2849: two highly selective dopamine D3 receptor antagonists.
Yuan J, Chen X, Brodbeck R, Primus R, Braun J, Wasley JW, Thurkauf A.
Bioorg Med Chem Lett (1998) 8 : 2715 -2718
PubMed 9873609 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.19 7.19

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL287198 1 7.19

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL287198 Ki = 65.0 nM 7.19