Assay Detail
Binding
CHEMBL669146
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of [3H]raclopride binding to human dopamine D2A receptor expressed in LtK cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | LtK |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Derivatives of (R)-2-amino-5-methoxytetralin: antagonists and inverse agonists at the dopamine D2A receptor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 6.38 | 6.38 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL65847 | — | — | 1 | 6.38 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL65847 | — | Ki | = | 415.0 | nM | 6.38 |