Assay Detail
Binding
CHEMBL669942
Review assay metadata, readout intent, target linkage, and publication context from the same page.
The compound was evaluated for the binding affinity towards Dopamine receptor D2 at high affinity state.
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Sus scrofa |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
(+/-)-3-Allyl-6-bromo-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3- benzazepin, a new high-affinity D1 dopamine receptor ligand: synthesis and structure-activity relationship.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 7.34 | 7.41 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL541559 | — | — | 1 | 7.41 |
| CHEMBL544115 | — | — | 1 | 7.26 |
| CHEMBL544118 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL541559 | — | Ki | = | 39.0 | nM | 7.41 |
| CHEMBL544115 | — | Ki | = | 55.0 | nM | 7.26 |
| CHEMBL544118 | — | Ki | = | 810000.0 | nM | - |