Assay Detail
Binding
CHEMBL670073
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity towards Dopamine receptor D2 by displacement of [3H]-Raclopride.
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
Synthesis, biological activity and quantitative structure-activity relationships of N-substituted-3,4-dihydro-2H-1-benzopyran derivatives
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 6.81 | 8.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL11592 | — | — | 1 | 8.00 |
| CHEMBL416523 | — | — | 1 | 7.53 |
| CHEMBL11425 | — | — | 1 | 7.17 |
| CHEMBL417608 | — | — | 1 | 5.75 |
| CHEMBL11262 | — | — | 1 | 5.59 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL11592 | — | IC50 | = | 10.0 | nM | 8.00 |
| CHEMBL416523 | — | IC50 | = | 29.51 | nM | 7.53 |
| CHEMBL11425 | — | IC50 | = | 67.61 | nM | 7.17 |
| CHEMBL417608 | — | IC50 | = | 1778.28 | nM | 5.75 |
| CHEMBL11262 | — | IC50 | = | 2570.4 | nM | 5.59 |