Assay Detail
Binding
CHEMBL670083
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Tested for the inhibitory activity against Dopamine D2 receptor in infected Sf9 cells
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Cell Type | Sf9 |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Iodinated 2-aminotetralins and 3-amino-1-benzopyrans: ligands for dopamine D2 and D3 receptors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 6.36 | 6.58 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL110239 | — | — | 1 | 6.58 |
| CHEMBL263282 | — | — | 1 | 6.49 |
| CHEMBL336851 | — | — | 1 | 6.26 |
| CHEMBL133085 | — | — | 1 | 6.11 |
| CHEMBL138015 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL110239 | — | Ki | = | 265.0 | nM | 6.58 |
| CHEMBL263282 | — | Ki | = | 324.0 | nM | 6.49 |
| CHEMBL336851 | — | Ki | = | 547.0 | nM | 6.26 |
| CHEMBL133085 | — | Ki | = | 784.0 | nM | 6.11 |
| CHEMBL138015 | — | Ki | > | 5000.0 | nM | - |