Assay Detail
Binding
CHEMBL670091
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The compound's binding affinity against Dopamine receptor D2
6
Total Activities
6
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
N-arylpiperazinyl-N'-propylamino derivatives of heteroaryl amides as functional uroselective alpha 1-adrenoceptor antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Log Ki | 5 | - | - |
| Ki | 1 | 6.90 | 6.90 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL90746 | — | — | 1 | 6.90 |
| CHEMBL329160 | — | — | 1 | - |
| CHEMBL88160 | — | — | 1 | - |
| CHEMBL420620 | — | — | 1 | - |
| CHEMBL91605 | — | — | 1 | - |
| CHEMBL89030 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL90746 | — | Ki | = | 125.89 | nM | 6.90 |
| CHEMBL329160 | — | Log Ki | = | 7.4 | uM | - |
| CHEMBL88160 | — | Log Ki | = | 8.1 | uM | - |
| CHEMBL420620 | — | Log Ki | = | 6.7 | uM | - |
| CHEMBL91605 | — | Log Ki | = | 6.4 | uM | - |
| CHEMBL89030 | — | Log Ki | = | 7.3 | uM | - |