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Assay Detail

CHEMBL670472

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Evaluated for Adrenoceptor from guinea pig left atrium by using isoproterenol as agonist.
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Cavia porcellus
Tissue Cardiac atrium
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Arylethanolamines derived from salicylamide with alpha- and beta-adrenoceptor blocking activities. Preparation of labetalol, its enantiomers, and related salicylamides.
Clifton JE, Collins I, Hallett P, Hartley D, Lunts LH, Wicks PD.
J Med Chem (1982) 25 : 670 -679
PubMed 6124636 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 2 8.81 8.81

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL27 PROPRANOLOL 4.0 1 8.81
CHEMBL597 PHENTOLAMINE 4.0 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL27 PROPRANOLOL Kd = 1.549 nM 8.81
CHEMBL597 PHENTOLAMINE Kd > 10000.0 nM -