Assay Detail
Binding
CHEMBL670673
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Compound was evaluated for affinity towards dopamine D2-like receptor in homogenate of caudate putamen tissue from rat brain
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Tissue | Caudate-putamen |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Cyclopentadienyltricarbonylrheniumbenzazepines: synthesis and binding affinity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 6.09 | 6.26 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL274577 | Cyclopentadienyltricarbonylrheniumbenzazepine (2`-CPTR-SCH-23390) | — | 1 | 6.26 |
| CHEMBL13325 | — | — | 1 | 6.23 |
| CHEMBL13632 | — | — | 1 | 5.95 |
| CHEMBL62 | SCH-23390 | — | 1 | 5.92 |
| CHEMBL427996 | Cyclopentadienyltricarbonylrheniumbenzazepine (3`-CPTR-SCH-23390) | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL274577 | Cyclopentadienyltricarbonylrheniumbenzazepine (2`-CPTR-SCH-23390) | Ki | = | 549.0 | nM | 6.26 |
| CHEMBL13325 | — | Ki | = | 583.0 | nM | 6.23 |
| CHEMBL13632 | — | Ki | = | 1120.0 | nM | 5.95 |
| CHEMBL62 | SCH-23390 | Ki | = | 1210.0 | nM | 5.92 |
| CHEMBL427996 | Cyclopentadienyltricarbonylrheniumbenzazepine (3`-CPTR-SCH-23390) | Ki | > | 10000.0 | nM | - |