Assay Detail
Binding
CHEMBL670676
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Ability to displace [3H]raclopride binding to cloned human Dopamine receptor D2A
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
(R)-11-hydroxy- and (R)-11-hydroxy-10-methylaporphine: synthesis, pharmacology, and modeling of D2A and 5-HT1A receptor interactions.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 6.86 | 7.38 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL53 | APOMORPHINE | 4.0 | 1 | 7.38 |
| CHEMBL119455 | — | — | 1 | 7.23 |
| CHEMBL53510 | — | — | 1 | 5.97 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL53 | APOMORPHINE | Ki | = | 41.9 | nM | 7.38 |
| CHEMBL119455 | — | Ki | = | 58.5 | nM | 7.23 |
| CHEMBL53510 | — | Ki | = | 1070.0 | nM | 5.97 |