Assay Detail
Binding
CHEMBL670964
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The compound was tested for binding affinity against dopamine receptor D2 using raclopride as radioligand
3
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Conformational properties of semirigid antipsychotic drugs: the pharmacophore for dopamine D-2 antagonist activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 8.19 | 9.18 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL300647 | — | — | 1 | 9.18 |
| CHEMBL45491 | — | — | 2 | 8.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL300647 | — | Ki | = | 0.66 | nM | 9.18 |
| CHEMBL45491 | — | Ki | = | 2.0 | nM | 8.70 |
| CHEMBL45491 | — | Ki | = | 200.0 | nM | 6.70 |