Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL671064

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibition of [3H]thymidine uptake by Dopamine receptor D2
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

D(2) dopamine receptor (CHEMBL217)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

3-[[(4-Aryl-1-piperazinyl)alkyl]cyclohexyl]-1H-indoles as dopamine D2 partial agonists and autoreceptor agonists.
Wustrow DJ, Smith WJ, Corbin AE, Davis MD, Georgic LM, Pugsley TA, Whetzel SZ, Heffner TG, Wise LD.
J Med Chem (1997) 40 : 250 -259
PubMed 9003524 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 8.55 8.55

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL423499 1 8.55

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL423499 EC50 = 2.8 nM 8.55