Assay Detail
Binding
CHEMBL671362
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Ability to displace [3H]-spiperone from CHO cells expressing human Dopamine receptor D2 was determined
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Cell Type | CHO |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Solid-phase synthesis of 2,3-disubstituted indoles: discovery of a novel, high-affinity, selective h5-HT2A antagonist.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 5.97 | 6.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL91205 | — | — | 1 | 6.05 |
| CHEMBL74355 | VOLINANSERIN | 3.0 | 1 | 5.89 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL91205 | — | Ki | = | 900.0 | nM | 6.05 |
| CHEMBL74355 | VOLINANSERIN | Ki | = | 1300.0 | nM | 5.89 |