Assay Detail
Binding
CHEMBL671449
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Inhibitory activity against the dopamine decarboxylase
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Synthesis of some novel potent and selective catechol O-methyltransferase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.30 | 4.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL168600 | — | — | 1 | 4.30 |
| CHEMBL353187 | — | — | 1 | 4.30 |
| CHEMBL169926 | — | — | 1 | 4.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL168600 | — | IC50 | = | 50000.0 | nM | 4.30 |
| CHEMBL353187 | — | IC50 | = | 50000.0 | nM | 4.30 |
| CHEMBL169926 | — | IC50 | = | 50000.0 | nM | 4.30 |