Assay Detail
Binding
CHEMBL671705
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Binding affinity for human dopamine receptor D4 using [125I]IABN as radioligand
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Conformationally-flexible benzamide analogues as dopamine D3 and sigma 2 receptor ligands.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 6.47 | 7.32 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL305366 | — | — | 1 | 7.32 |
| CHEMBL64176 | — | — | 1 | 6.58 |
| CHEMBL59713 | — | — | 1 | 6.10 |
| CHEMBL61789 | — | — | 1 | 5.87 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL305366 | — | Ki | = | 47.9 | nM | 7.32 |
| CHEMBL64176 | — | Ki | = | 265.0 | nM | 6.58 |
| CHEMBL59713 | — | Ki | = | 800.0 | nM | 6.10 |
| CHEMBL61789 | — | Ki | = | 1345.0 | nM | 5.87 |