Assay Detail
Binding
CHEMBL671770
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In vitro binding affinity against Dopamine transporter in LLC-PK1 cell membranes.
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Sus scrofa |
| Cell Type | LLC-PK1 |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Sodium-dependent dopamine transporter (CHEMBL238) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
A new single-photon emission computed tomography imaging agent for serotonin transporters: [123I]IDAM, 5-iodo-2-((2-((dimethylamino)methyl)phenyl)thio)benzyl alcohol.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 6.95 | 6.95 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL361259 | — | — | 1 | 6.95 |
| CHEMBL278165 | — | — | 1 | - |
| CHEMBL114275 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL361259 | — | Ki | = | 112.0 | nM | 6.95 |
| CHEMBL278165 | — | Ki | > | 10000.0 | nM | - |
| CHEMBL114275 | — | Ki | > | 10000.0 | nM | - |