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Assay Detail

CHEMBL672229

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Binding
Binding affinity towards cloned human dopamine D2 receptor was determined
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

D(2) dopamine receptor (CHEMBL217)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Identification of a novel series of selective 5-HT7 receptor antagonists.
Forbes IT, Cooper DG, Dodds EK, Douglas SE, Gribble AD, Ife RJ, Lightfoot AP, Meeson M, Campbell LP, Coleman T, Riley GJ, Thomas DR.
Bioorg Med Chem Lett (2003) 13 : 1055 -1058
PubMed 12643910 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 6.63 6.63

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL273921 1 6.63

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL273921 Ki = 234.42 nM 6.63