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Assay Detail

CHEMBL672346

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity against cloned human Dopamine receptor D2 was evaluated
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

D(2) dopamine receptor (CHEMBL217)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Discovery of potent and selective small molecule NPY Y5 receptor antagonists.
Islam I, Dhanoa D, Finn J, Du P, Walker MW, Salon JA, Zhang J, Gluchowski C.
Bioorg Med Chem Lett (2002) 12 : 1767 -1769
PubMed 12067557 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.20 7.20

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL299879 1 7.20

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL299879 Ki = 63.0 nM 7.20