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Assay Detail

CHEMBL672487

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Functional
Compound was evaluated for the binding affinity against [3H]U-86,170-labeled dopamine receptor D2 in cloned CHO cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Cell Type CHO
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

D(2) dopamine receptor (CHEMBL217)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Centrally acting serotonergic and dopaminergic agents. 1. Synthesis and structure-activity relationships of 2,3,3a,4,5,9b-hexahydro-1H-benz[e]indole derivatives.
Lin CH, Haadsma-Svensson SR, Lahti RA, McCall RB, Piercey MF, Schreur PJ, Von Voigtlander PF, Smith MW, Chidester CG.
J Med Chem (1993) 36 : 1053 -1068
PubMed 8097537 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 6.41 6.41

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL416519 1 6.41

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL416519 Ki = 392.0 nM 6.41